There aren't any adequate and nicely-managed scientific studies of propoxyphene with acetaminophen in pregnant Women of all ages. Even though you'll find restricted details while in the released literature, adequate animal reproduction experiments haven't been executed with propoxyphene or acetaminophen.
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Coadministration with agents that induce CYP3A4 exercise may well lessen the efficacy of propoxyphene. Strong CYP3A4 inducers such as rifampin could lead to Increased metabolite (norpropoxyphene) amounts.
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Snooze Disturbance: In this sort of conditions, you are able to seek the advice of with all your medical doctor. As they would both propose you A different medicine or lower down your dosage.
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Clients need to be encouraged that when they are already getting therapy with Darvocet-N (propoxyphene napsylate and acetaminophen) for quite a lot of months and cessation of therapy is indicated, it could be correct to taper the Darvocet-N (propoxyphene napsylate and acetaminophen) dose, instead more info of abruptly discontinue it, due to the risk of precipitating withdrawal signs or symptoms.
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